At present, sprays and aerosols are widely used in medical practice. These dosage forms are often used for external use, they are intended for applying the drug to the wound, on the skin, on the mucous membranes, as well as for inhalation. In sprays and many aerosols, the principle of drug delivery is approximately the same, which is contained there in the form of liquid and solid particles suspended in a gaseous medium. Since both of these forms have the same filing principle, they are often confused. However, there are certain differences between them that must be considered when choosing a dosage form.
Spray sprayed using a mechanical pump, while the pressure in the bottle and the pressure outside it are the same.
Aerosol is sprayed due to the formation of excessive pressure in the bottle, it can be continuous or dispensing action.
At the time of use, both spray and aerosol create a stable atomization of particles. For aerosol, they are 2-5 microns, for spray - more than 5 microns. The bottles in either case are hermetically sealed, so the possibility of air or contamination getting into them is completely excluded. Aerosols and sprays are successfully used in medical practice for spraying various drugs. So, for example, anti-burn drugs (Panthenol, Olazol) are produced in the form of an aerosol. In sprays today you can find many medicines intended for the treatment of the nose (Aquamaris, Dolphin).
- The spray is sprayed using a mechanical pump, while the pressure in the bottle is equal to atmospheric. The aerosol is supplied under pressure.
- Spray sprays larger particles (more than 5 microns), aerosol - fine (2-5 microns).