Difference between Amoxiclav and Amoxicillin.

Our health is our hands, which is why we try to do our best to cure the disease as soon as possible. Going to an appointment with a doctor, we mentally prepare for the fact that the doctor will prescribe medication and what kind of medicine it will be depends on the disease itself. That is why we often ask ourselves the question: "Which of the antibiotics is better, Amoxicillin or Amoxiclav, and what is the difference between them?"


Amoxiclav - an antibiotic that has been used in clinical practice for about thirty years. This is a combined drug, it belongs to the category of semi-synthetic penicillins. Amoxiclav contains amoxicillin and clavulanic acid. Amoxicillin has a bactericidal effect, inhibiting bacterial walls, and clavulanic acid together with it forms a stable complex, as a result of which a decrease in its enzymatic hydration is prevented and a guaranteed antibacterial effect is ensured. The bactericidal effect of the drug covers a wide range of bacteria, including gram-positive and gram-negative.

Amoxicillin is an antimicrobial drug from the group of semi-synthetic penicillins, it has a bactericidal effect against gram-positive microorganisms. The drug is perfectly absorbed when taken orally and penetrates into body fluids. The maximum concentration of Amoxicillin in the blood is reached 2 hours after ingestion, then decreases rapidly. The drug is used to treat infections of the upper and lower respiratory tract, kidney and urinary tract, gynecological infections, as well as diseases of the skin and other tissues.


The difference between these drugs lies in the presence of clavulanic acid, which significantly expands the spectrum of action of the main substance. Amoxicillin is a derivative of ampicillin, it has a bactericidal effect by acting on the cell membrane of the bacterium. The obvious disadvantage of this drug is its complete defenselessness against the production of lactamase, it is this problem that clavulanic acid added to Amoxicillin solves. Currently, the drug is rarely used to treat staphylococcal infections, since pathogens develop resistance to the drug.

Conclusions TheDifference.ru

  1. Amoxiclav is a semi-synthetic combined drug, consisting of Amoxicillin and clavulanic acid. Amoxicillin is a semi-synthetic antibiotic (the active ingredient is Amoxicillin).
  2. Amoxiclav has a broader spectrum of action due to clavulanic acid. Amoxicillin is used to treat streptococcal infections, but it is not active against staphylococci.
  3. Amoxiclav is more expensive, amoxicillin is orders of magnitude cheaper.